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. 2017 Jul 24;6(7):e363. doi: 10.1038/oncsis.2017.63

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Copyright © 2017 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ZNF687 overexpression correlates with HCC progression and recurrence. (a) ZNF687 mRNA expression profile in HCC tissues and adjacent cancer tissues and in cirrhosis liver tissue from the GSE57957 (P<0.05) and GSE56140 data sets (P<0.01). (b) ZNF687 mRNA expression profile in HCC tissues (n=351) and normal liver tissues (n=50) from TCGA data set (P<0.001). (c) Kaplan–Meier analysis of overall survival curves and relapse-free survival curves from TCGA data set for patients with HCC with relatively low or relatively high ZNF687 expression levels (P<0.05). (d) GSEA plot showing that high ZNF687 expression correlated positively with recurrence gene signatures in published TCGA expression profiles of patients with HCC.