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. 2017 Jul 24;6(7):e363. doi: 10.1038/oncsis.2017.63

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Copyright © 2017 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ZNF687 enhances tumorigenesis and stem cell-like traits of HCC in vivo. (a, b) Representative images of tumor-bearing mice (a) and tumors from all mice in each group (b). (c) Mean tumor volumes were measured on the indicated days. (d) Mean tumor weights. (e) Cells (1 × 10⁴, 1 × 10³ or 1 × 10²) were implanted into NOD/SCID mice. Representative images of tumorigenesis in each group are shown. (f) Histogram shows the mean tumor weights of each group (n=6 per group). *P<0.05. Mean tumor volumes are plotted. (g) Tumor formation rate of dilutions used and estimated percentage of tumor-initiating cells (TIC).