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(A) Western Blot showed JQ1 or JQ1 combined ubenimex treatment on HEXIM1 and autophagy marker LC3B, P62 expression. Pharmacologic autophagy stimulator Rapamycin (10nm) attenuated this effect on degradation of HEXIM1. (B) Immunofluorescence staining of HEXIM1 on JQ1 or JQ1 combined ubenimex treatment on U87M cells. (C) Quantitation of B. *: P<0.05 vs control. #, P<0.05 vs JQ1+ubenimex.
