Table 2.
Clinical and hematological features of patients receiving a diagnosis of ICUS grouped according to mutation status compared with features of patients receiving a diagnosis of MDS
| Variable | ICUS | MDS | P value | ||
|---|---|---|---|---|---|
| ICUS unmutated | CCUS low predictive pattern | CCUS high predictive pattern | |||
| No. of patients | 97 | 24 | 32 | 233 | |
| Age, median (range), y | 53 (18-88) | 68 (18-86) | 68 (41-86) | 69 (27-91) | <.001 |
| Sex, M/F | 44/53 | 12/9 | 25/11 | 142/91 | .012 |
| Hemoglobin, median (range), g/dL | 12.7 (8.6-15.7) | 12.9 (9.7-15.4) | 11.9 (8.2-14.8) | 9.9 (5-15.6) | <.001 |
| Mean cell volume, median (range), fL | 92 (78-110) | 92 (82-102) | 92 (78-118) | 98 (63-124) | <.001 |
| White blood cell count, median (range), ×109/L | 3.72 (0.96-12.4) | 3.72 (1.75-9.5) | 3.94 (0.56-12.2) | 4.26 (0.7-15.82) | .72 |
| Absolute neutrophil count, median (range), ×109/L | 1.85 (0.68-9.2) | 1.88 (0.61-5.67) | 1.70 (0.61-6.22) | 2.4 (0.18-12.62) | .89 |
| Platelet count, median (range), ×109/L | 151 (20-496) | 117 (71-206) | 137 (23-355) | 129 (6-495) | .46 |