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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Microcirculation. 2017 Aug;24(6):10.1111/micc.12369. doi: 10.1111/micc.12369

Table 1.

Summary of the biological effects of the peptide fragments contained within the 1st type III repeat of plasma fibronectin, (FNIII1).

Peptide Peptide sequence Survival activitya FN/PDGF-BB binding inhibitionb Control c
Dose (%) Max dilation
Stress c
Dose (%) Max dilation
EVA-1 PSHISKYILRWRPK Yes 95.5% 10−9M 22% 10−13M 32%
P18 YILRWRPK No 26% 10−8M 26%
P7 ILRWRPK No 0.1% 10−8M 28% 10−12M 29%
P39 LRWRPK No 0.0% 10−11M 8%
P37 RWRPK No 0.0% 10−11M 19% 10−15M 45%
a

(ref #17, Lin, et al., 2011);

b

(Ref #18, Lin, et al., 2014; Ref #35, Zhu, et al., 2014);

c

present study, terminal arterioles.