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. 1985 Oct;4(10):2499–2504. doi: 10.1002/j.1460-2075.1985.tb03962.x

Astrocytes support incomplete differentiation of an oligodendrocyte precursor cell.

G Keilhauer, D H Meier, S Kuhlmann-Krieg, J Nieke, M Schachner
PMCID: PMC554535  PMID: 4054097

Abstract

Glial fibrillary acidic protein-positive astrocytes, but not neurons or fibroblasts, support the differentiation of an oligodendroglial precursor cell expressing O4 antigen and vimentin into an O4 antigen-positive, but vimentin-negative oligodendrocyte. Further maturation into galactocerebroside (O1)-positive oligodendrocytes is, however, not achieved under the culture conditions used, neither in the presence of astrocytes nor neurons.

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Selected References

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