Table 2. Dexmedetomidine alleviated LPS-induced downregulation of antioxidant genes in the lung of rats.
Item | Cont | LPS | Dex |
---|---|---|---|
NQO1 | 1.00 ± 0.09a | 0.79 ± 0.08b | 0.88 ± 0.11ab |
NQO2 | 1.00 ± 0.06 | 1.06 ± 0.13 | 1.11 ± 0.17 |
CAT | 1.00 ± 0.13 | 0.94 ± 0.12 | 0.86 ± 0.13 |
GPX1 | 1.00 ± 0.09a | 0.75 ± 0.08b | 0.84 ± 0.07b |
GPX2 | 1.00 ± 0.09a | 0.85 ± 0.09b | 0.93 ± 0.11ab |
SOD1 | 1.00 ± 0.12a | 0.72 ± 0.08b | 0.94 ± 0.16a |
SOD2 | 1.00± 0.11 | 1.27 ± 0.16 | 0.95 ± 0.08 |
Data are presented as mean ± SEM. The values having different superscript letters were significantly different (P < 0.05).