Table 2.

Imaging findings.

Imaging Exam	Characteristic Findings	Availability
Cardiac echocardiography [45,46,49,50,51,52,53,54]	Lower early diastolic tissue Doppler velocities Longer isovolumic relaxation time Shorter isovolumic contraction time Lower peak systolic wall motion velocity Lower global peak systolic strain Lower global deformation values	Clinical work-up
Cardiac MR [55,56,57,58,59]	Low T1 LGE in the posterior and lateral walls	Clinical work-up
Cerebral MR [63,64,65,66,67,68,69,70,71,72,73,74,75]	White matter lesions on T2-weighted MRI Basilar artery dolichoectasia Pulvinar sign on T1 Hippocampus atrophy	Clinical work-up
Transcranial Doppler [61]	Small vessel disease and abnormal cerebral autoregulation; posterior cortical vascular dysfunction	Clinical work-up
PET/MR [60,84]	Cardiac: distinguish scar from fibrosis associated with active inflammation. Cerebral: No additional information to MR isolated	Experimental studies