Table 3.
Number of patients who experienced toxicities (n = 30).
| Toxicity type | Toxicity grade | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Hematologic | ||||
| Anemia | 12 | 5 | 0 | 0 |
| Thrombocytopenia | 11 | 3 | 0 | 0 |
| Neutropenia | 1 | 3 | 6 | 1 |
| Non-hematologic | ||||
| Abdominal pain | 1 | 4 | 3 | 0 |
| ALT elevation | 13 | 2 | 1 | 0 |
| Alkaline phosphatase elevation | 5 | 1 | 1 | 0 |
| Anorexia | 6 | 15 | 2 | 0 |
| Ascites | 0 | 0 | 1 | 0 |
| AST elevation | 18 | 1 | 2 | 0 |
| Total bilirubin elevation | 3 | 2 | 1 | 0 |
| Colitis | 0 | 0 | 1 | 0 |
| Creatinine elevation | 2 | 0 | 0 | 0 |
| Dehydration | 3 | 8 | 1 | 0 |
| Diarrhea | 17 | 3 | 3 | 0 |
| Dysesthesia | 20 | 4 | 2 | 0 |
| Fatigue | 3 | 14 | 7 | 0 |
| Headache | 1 | 1 | 1 | 0 |
| Hypertension | 0 | 4 | 7 | 0 |
| Hyponatremia | 1 | 0 | 2 | 0 |
| Nausea | 10 | 11 | 2 | 0 |
| Noncardiac chest pain | 0 | 0 | 1 | 0 |
| Pancreatitis | 0 | 0 | 1 | 0 |
| Peripheral neuropathy | 18 | 3 | 2 | 0 |
| Pneumonitis | 0 | 0 | 1 | 0 |
| Portal Hypertension | 0 | 0 | 1 | 0 |
| Proteinuria | 11 | 1 | 0 | 0 |
| Syncope | 0 | 0 | 1 | 0 |
| Thromboembolic event | 0 | 0 | 1 | 0 |
| Vomiting | 13 | 3 | 0 | 0 |
| Weight loss | 6 | 1 | 0 | 0 |