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. Author manuscript; available in PMC: 2018 Jul 5.
Published in final edited form as: Neuron. 2017 Jun 22;95(1):169–179.e3. doi: 10.1016/j.neuron.2017.06.007

Figure 6. Removal of PNNs in the auditory cortex after fear conditioning, results in decreased fear expression observed after 24 and 48 hours but not 30 minutes after fear conditioning.

Figure 6

ChABC or saline was injected into the auditory cortex of mice within 30 minutes after auditory fear conditioning. No differences were observed in fear acquisition (A) or fear expression 30 minutes after fear conditioning (B) between saline and ChABC groups (C). Decreased fear expression was observed in ChABC injected mice in comparison to controls at 24 hours after fear conditioning (D) wherein significant differences between groups were observed during CS1–5, CS6–10 and CS11–15 (E) and at 48 hours after fear conditioning (F). No significant differences between groups were observed after binning according to CS number (G). *P < 0.05 vs. vehicle. All values are means ±SEM