Table 2.
The polymerase proteins PB2, PB1 and PA of H7N3 and H7N9 virus affect replication in MDCK cells.
| Virus | Substituted gene-segments | Virus Titer (log10/ml) |
|---|---|---|
| H7N3 | 5.9 (1.0) | |
| PB2, PB1, PA | 4.4 (1.1) * | |
| HA, NA | 6.4 (0.5) | |
| NS | 5.1 (0.6) | |
| H7N9 | 4.5 (0.8) | |
| PB2, PB1, PA | 6.4 (0.7) # | |
| HA, NA | - | |
| NS | 3.8 (0.4) |
Results are the average and standard deviation of the log10-transformed virus titers 24 hours after inoculation of MDCK cells derived from at least two independent experiments.
*
= P<0.05 compared to H7N3 virus.
#
= P<0.05 compared to H7N9 virus.
“-”, no data.