Table 1.
Comparison of demographic, clinic and pathological characteristics of Her-2 positive and negative patients.
| Variables | HER-2 negative n = 99 | HER-2 positive n = 159 | P |
|---|---|---|---|
| Age(year), mean±sd. | 50.06 ± 13 .77 | 49.23 ± 10 .45 | 1.000 |
| Onset time, n (%) | 0.134 | ||
| Pre-menopause | 51(51.52) | 97(61.01) | |
| Post-menopause | 48(48.48) | 62(38.99) | |
| Tumor location, n (%) | 0.430 | ||
| Left | 43(43.43) | 81(50.94) | |
| Right | 55(55.56) | 77(48.43) | |
| Bilateral | 1(1.01) | 1(0.63) | |
| First symptoms | 0.550 | ||
| Lump | 92(92.93) | 152(95.60) | |
| Nipple discharge | 4(4.04) | 4(2.52) | |
| Axillary lump | 2(2.02) | 3(1.89) | |
| Calcification | 1(1.01) | 0(0.00) | |
| Vessel carcinoma embolus, n (%) | 0.126 | ||
| No | 90(90.91) | 134(84.28) | |
| Yes | 9(9.09) | 25(15.72) | |
| Pathological type, n (%) | 0.002 | ||
| IDC | 75(76.53) | 141(88.68) | |
| Other | 23(23.47) | 18(11.32) | |
| Histological grade, n (%) | 0.001 | ||
| 1 | 14(14.14) | 6(3.77) | |
| 2 | 57(57.58) | 81(50.94) | |
| 3 | 28(28.28) | 72(45.28) | |
| Diameter of lumps, n (%) | 0.036 | ||
| T1 | 58(58.59) | 67(42.14) | |
| T2 | 37(37.37) | 82(51.57) | |
| T3 | 4(4.04) | 10(6.29) | |
| axillary lymph node metastasis, n (%) | 0.024 | ||
| N0 | 66(66.67) | 78(49.06) | |
| N1 | 20(20.20) | 45(28.30) | |
| N2 | 4(4.04) | 19(11.95) | |
| N3 | 9(9.09) | 17(10.69) | |
| pTNM staging, n (%) | 0.033 | ||
| 0–I | 42(42.42) | 44(27.67) | |
| II | 45(45.45) | 83(52.20) | |
| III | 12(12.12) | 32(20.13) |