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. Author manuscript; available in PMC: 2017 Aug 12.
Published in final edited form as: Science. 2014 Oct 17;346(6207):363–368. doi: 10.1126/science.1259077

Fig. 3. RPL23A-reactive TH cells in R7–39 mice.

Fig. 3

(A) Cytokine production by CD4+ T cells from regional lymph nodes (RLNs) of R7–39 or R1–23 mice after in vitro stimulation with recombinant RPL23A or control glutathione S-transferase (GST) protein. Stim, Stimulation. (B) Percentages of cytokine-producing CD4+ T cells in A (n=3). (C) Cytokine amounts in culture supernatants in A (n=6). (D) IL-17A production by RPL23A-stimulated lymphocytes from R7–39 mice in the presence or absence of anti-MHC class I or class II (anti-I-A/E) blocking antibody (n=6). (E) IL-17A production by lymphocytes stimulated with recombinant RPL23A or control GST proteins (n=8). Lymphocytes were taken from SKG or BALB/c mice with or without mannan treatment. Data are from 3 (A and B), 6 (C and D) or 8 (E) mice. In B, results are shown as the means±s.d. For C–E, horizontal bars indicate the means. *P<0.05 (Kruskal-Wallis test followed by Steel-Dwass test). NS, not significant. Results represent two independent experiments.