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. Author manuscript; available in PMC: 2017 Nov 3.
Published in final edited form as: Nature. 2016 Oct 5;539(7627):89–92. doi: 10.1038/nature19813

Extended Data Figure 3. The distal enhancer located in the Hoxa11 intron is bound by HOXA13 and HOXD13 in distal limb cells and its activity is increased by HOXA13 in 293T cells.

Extended Data Figure 3

a, Integrative genomics viewer (IGV) screenshot showing HOXA13 and HOXD13 ChIP-seq data at the Hoxa11 locus. These ChIP-seq data were obtained using chromatin from distal forelimb buds of wild-type E11.5 mouse embryos (R. Sheth et al., manuscript submitted). b, Transfection assay shows HOXA13 dependent activation of Hoxa11 intron driving reporter gene expression. Two-tailed Tukey’s multiple comparisons test was performed. Error bars indicate s.d (n = 3). RQ, relative quantification.