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. Author manuscript; available in PMC: 2017 Nov 3.
Published in final edited form as: Nature. 2016 Oct 5;539(7627):89–92. doi: 10.1038/nature19813

Extended Data Figure 4. Individual inactivation of Hoxa13 or Hoxd13 is not sufficient to fully abrogate antisense transcription in distal limbs.

Extended Data Figure 4

a, b, Whole-mount in situ hybridization, using probe A (see Fig. 1) to detect all antisense transcripts, on Hoxd13−/− (a) and Hoxa13−/− (b) mouse limb buds at E11.5. Antisense transcription in distal limbs remains robust in both mutants but a clear reduction is seen in the distal Hoxa13−/− limbs. Original magnification, ×31.5.