. 2017 Aug 14;5:e3662. doi: 10.7717/peerj.3662

Table 1. The influence of hypoxia preconditioning combined with microtubule stabilization on cardiomyocyte injury and energy generation.

The LDH content of cardiomyocytes (IU/g protein, mean ± SD) was detected after treatment with different interventions for 12 h. The PFK (IU/g protein, mean ± SD), ATP, and ADP (mg/g protein, mean ± SD) content. E–F, The PK and HK content (IU/g protein, mean ± SD). The above data showed that paclitaxel could enhance the myocardial protective effect of hypoxia preconditioning.

	LDH	ADP	ATP	PK	HK	PFK	ROS
N	262.3± 88.80^a^,^b	4.75 ± 0.621^a^,^b	26 ± 1.12^a^,^b	13.41 ± 1.50^a^,^b	15.33 ± 1.30^a^,^b	21 ± 1.41^a^,^b	2.39 ± 0.45^a^,^b
H	1663 ± 155.8^b^,^c	14.91 ± 1.08^b^,^c	11.58 ± 0.99^b^,^c	479.5 ± 39.64^b^,^c	138.9 ± 18.90^c	175.7 ± 11.39^b^,^c	7.70 ± 0.68^b^,^c
HPC	759.6 ± 132.7^a^,^c	12.41 ± 0.79^a^,^c	18.41 ± 1.16^a^,^c	687.7 ± 55.30^a^,^c	133.7 ± 12.54^c	215.4 ± 9.74^c	3.90 ± 0.31^a
HT5	1088.9 ± 122.3^a^,^b^,^c	12.33 ± 1.30^a^,^c	12.83 ± 1.02^a^,^c	803.2 ± 51.28^a^,^c	141.3 ± 13.03^c	154.5 ± 11.42^b^,^c	6.25 ± 0.23^a^,^b^,^c
HT10	956.0 ± 135.5^a^,^c	13.50 ± 0.52^a^,^c	15.41 ± 0.90^a^,^c	879.6 ± 65.79^a^,^c	152.8 ± 6.16^c	181.2 ± 9.81^b^,^c	5.10 ± 0.33^a^,^b^,^c
HT15	1091.5 ± 162.8^a^,^c	15.83 ± 1.58^a^,^b^,^c	10.50 ± 1.50^a^,^b^,^c	683.3 ± 87.68^a^,^c	133.9 ± 12.39^c	139.4 ± 16.78^b^,^c	6.25 ± 0.17^a^,^b^,^c
HPC + HT10	393.7 ± 130.9^a^,^b^,^c^,^d	5.83 ± 0.71^a^,^b^,^c^,^d	23.16 ± 1.52^a^,^b^,^c^,^d	1106.8 ± 85.64^a^,^b^,^c^,^d	205.1 ± 12.11^a^,^b^,^c^,^d	263.8 ± 13.82^a^,^b^,^c^,^d	3.20 ± 0.49^a^,^b^,^c^,^d

Notes.

Significantly different from the H group.

Significantly different from the HPC group.

Significantly different from the N group.

Significantly different from the HT10 group.