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. 2017 Jun 19;206(4):1747–1761. doi: 10.1534/genetics.117.203521

Figure 3.

Figure 3

Conservation and evolution of MIG-13 between C. elegans and O. tipulae. (A) Typical phenotype of a Oti-cov-3 mutant, shown in a Nomarski picture and an interpretation cartoon below: an anterior shift (1° fate shifted from P6.p to P5.p) is coupled to a reduced competence of vulva precursor cells. * indicates Pn.p cells with a modified fate compared to the wild type. (B) A cov-3-like phenotype can be observed at very low frequency in a mig-13 null mutant, Cel-mig13(mu225), of C. elegans. (C) Reduced competence of P3,4,8.p cells in Cel-mig-13(mu225) is indicated by increased frequency of 4° fate vs. 3° fate. WT, wild type.