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. 2017 Aug 1;4(4):275–282. doi: 10.1089/lgbt.2016.0135

Cognitive and Behavioral Resilience Among Young Gay and Bisexual Men Living with HIV

Sophia A Hussen 1,,2,, Gary W Harper 3, Caryn RR Rodgers 4, Jacob J van den Berg 5, Nadia Dowshen 6, Lisa B Hightow-Weidman 7
PMCID: PMC5564056  PMID: 29792564

Abstract

Purpose: HIV/AIDS disproportionately affects young gay, bisexual, and other men who have sex with men (Y-GBMSM). Resilience remains understudied among Y-GBMSM living with HIV, but represents a potentially important framework for improving HIV-related outcomes in this population. We sought to explore cognitive and behavioral dimensions of resilience and their correlates among Y-GBMSM to gain insights to inform future interventions.

Methods: Our study sample consisted of 200 Y-GBMSM living with HIV enrolled in a multisite study of the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). Participants completed a one-time, self-administered structured questionnaire, including validated scales capturing a range of cognitive, behavioral, demographic, and psychosocial data. Utilizing these data, we examined cognitive and behavioral dimensions of resilience and their potential psychosocial correlates using linear regression modeling.

Results: Multiple regression analyses demonstrated that education, stigma, social support, ethnic identity, internalized homonegativity, and behavioral resilience were statistically significant predictors of cognitive resilience (P < 0.001, R2 = 0.678). Social support satisfaction and cognitive resilience were significant predictors of behavioral resilience (P < 0.001, R2 = 0.141).

Conclusions: Our findings point to potential strategies for incorporating resilience-promoting features into future interventions to support Y-GBMSM living with HIV. Specifically, strengths-based interventions in this population should seek to enhance social support, promote positive identity development, and encourage education. Future research can also seek to utilize and refine our measures of resilience among youth.

Keywords: : adolescents, HIV/AIDS, resilience, sexual minority health

Introduction

Although HIV incidence is stable in the United States overall, rates continue to increase among youth aged 13–24, who make up 26% of new diagnoses.1 This increase is primarily driven by new diagnoses among young gay, bisexual, and other men who have sex with men (Y-GBMSM); 72% of all new infections among GBMSM occur among persons aged 13–24.2 Given the large numbers of Y-GBMSM diagnosed with HIV each year in the United States, there is a critical need to improve our understanding of influences on health-related behaviors in this population.

Of the studies that focus exclusively on the health behaviors of Y-GBMSM, most utilize a risk or deficit paradigm, concentrating on risky behaviors that influence HIV acquisition or transmission (e.g., illicit drug use, inconsistent condom use).3–6 Although such studies provide important information, some have alternatively called for strengths-based approaches to research involving Y-GBMSM and sexual minority populations more generally.7–9 Such strengths-based research falls into a long tradition of utilizing resilience as a critically important lens through which to view adolescent and young adult health and development.10

Resilience is defined most succinctly as positive adaptation in the context of adversity.9,11,12 Our theoretical framing of resilience builds primarily on the work of Fergus and Zimmerman, but is also consistent with other foundational work in the field.11,13,14 Resilience refers not simply to the achievement of positive outcomes in the setting of risk but also to the actual adaptive processes that enable these outcomes. The influences on resilient adaptation have been characterized as “promotive factors,” which include intrinsic assets within the individual (e.g., self-esteem) and extrinsic resources, which are external to an individual (e.g., social support).13 Resilience and the promotive factors that enable it are generally described with respect to specific populations and risk behaviors, and the positive effects of such factors in one setting are not necessarily generalizable to others.

Resilience is a particularly important framework to examine among Y-GBMSM living with HIV, who are likely to face high levels of adversity related to multiple stigmatized identities. Despite these significant challenges, we have observed Y-GBMSM living with HIV to display adaptive coping skills and achieve favorable health outcomes in our prior work.8,9,15 Improving our understanding of resilience in these youth has the potential to inform effective interventions that enhance positive adaptation as opposed to simply mitigate risk.

Based on prior research, certain constructs can be hypothesized to function as either promotive or risk-enhancing factors among Y-GBMSM living with HIV.16 Specifically, positive identity development and social support emerge as likely promotive factors. Identity development is central in the lives of all adolescents, and these youth are living with multiple salient identities—sexual minority identity, HIV-positive identity, and often ethnic minority identity. Positive views of one's own ethnic identity have been previously linked with resilience in studies of minority youth, with respect to avoidance of violent behavior.17 In another study of Y-GBMSM, those who identified as heterosexual or bisexual, exhibited lower rates of resilience than those who identified as gay.18 A prior analysis from our parent study also highlighted associations between ethnic identity and engagement in HIV care among Y-GBMSM living with HIV.15 Social support is another resilience resource that is highlighted in many youth populations, across a range of behaviors.13 For example, peer and family support has been shown to mitigate the negative effects of violence.19 In one particularly relevant study, Kubicek et al. described resilience among Black Y-GBMSM participating in the predominantly Black and gay House/Ball subculture. They found that participation in the House/Ball community positively built on youth's intersecting minority identities while also enhancing social support.12

In many resilience-focused studies, the existence of resilience is inferred by documenting favorable outcomes among a population known to be at risk. However, scholars in the field have also developed and tested measures of resilience to assess resilience processes more directly.20–22 While no gold standard currently exists, most of these scales examine promotive factors (both intrinsic assets and extrinsic resources) that constitute resilience processes, which enhance an individual's ability to withstand adversity.

To measure resilience in our current analysis, we drew specifically on descriptions of resilience in our own sample of Y-GBMSM living with HIV. A previous qualitative analysis from our parent study (described in the next section) identified and described four dimensions of resilience within this group: (1) engaging health promoting cognitive processes; (2) enacting healthy behavioral practices; (3) enlisting social support; and (4) empowering other gay/bisexual youth (Fig. 1).8 The relationship between these dimensions was often temporal, with cognitive resilience leading to positive behavioral change. Building on these findings, the goal of the present analysis was to quantitatively examine these cognitive and behavioral dimensions of resilience and their correlates among Y-GBMSM living with HIV.

FIG. 1.

FIG. 1.

Dimensions of resilience among young gay, bisexual, and other men who have sex with men. Adapted with permission from: Harper et al.8

Methods

Study design and procedures

This analysis is derived from a multisite, cross-sectional study conducted by the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The parent study, ATN 070 (“Psychosocial Needs of HIV+ Young Men who Have Sex with Men”), was a mixed-methods examination of the psychosocial and developmental needs of Y-GBMSM living with HIV. Data collection was conducted at 14 geographically diverse ATN clinical sites between March and June of 2009. Young men aged 16–24 who were living with HIV and enrolled in HIV care at ATN-affiliated clinics were eligible to participate. Inclusion criteria were as follows: (1) male sex assigned at birth and identification as male at enrollment; (2) living with HIV; (3) HIV acquired horizontally through sexual or substance use behavior; (4) age 16–24; (5) ability to understand English; and (6) at least one sexual encounter with a male during the previous year (by self-report). On verification of eligibility, coordinators obtained signed consent and enrolled participants in the study. Waivers of parental consent were granted by the institutional review boards (IRBs), to avoid selection bias that could result from recruiting only those youth whose parents were aware/supportive of their sexual identity. Each participant completed an audio computer-assisted self-interview (ACASI) containing the measures described below. In addition, a subset of participants underwent qualitative interviews that led to the description of the dimensions of resilience depicted in Figure 1.8 The ATN 070 protocol was approved by the IRB at each site. IRB approval was not required for the analysis presented here, which was a secondary analysis of deidentified data. Compensation for participation was determined by each site.

Outcome measures

We derived two quantitative outcome measures from the ACASI questionnaire that aligned conceptually with the dimensions of resilience depicted in Figure 1.8 For the purposes of this analysis, we divided Harper's processes into cognitive resilience (which included “Engaging Health Promoting Cognitive Processes” in the original article) and behavioral resilience (a combination of “Enacting Healthy Behavioral Practices,” “Enlisting Social Support,” and “Empowering other gay/bisexual youth”; Table 1).

Table 1.

Selection of Measures to Approximate Cognitive and Behavioral Resilience

Description of resilience processes from Harper et al. qualitative analysis of Y-GBMSM living with HIV8 Scale or questions used to quantify the resilience dimensions in current analysis
Cognitive dimensions of resilience
 Re-evaluating life goals Time Perspective Inventory: Future Orientation Subscale23
  Assesses the degree to which respondents are striving for future goals and rewards
 Gaining a sense of control Life Outcome Expectancies Scale
  Measures respondents' perceived control over life circumstances and perceived likelihood of reaching life milestones
 Taking responsibility for health outcomes Illness Cognition Questionnaire24
  Measures helplessness, acceptance, and perceived benefits of living with a chronic illness
Behavioral dimensions of resilience
 Enacting healthy behavioral practices Have you…
  Increased exercise?
  Changed your diet?
  Quit/reduced smoking?
  Etc.
 Enlisting social support Have you…
  Joined a support group?
  Begun to attend church/synagogue/temple?
  Etc.
 Empowering other gay/bisexual youth Have you…
  Educated others about HIV?

Y-GBMSM, young gay, bisexual, and other men who have sex with men.

In the qualitative study by Harper et al., three cognitive processes were described: (1) re-evaluating life goals, (2) gaining a sense of control, and (3) taking responsibility for health outcomes.8 To approximate these specific subthemes, we assessed cognitive resilience using a composite measure consisting of the Future Orientation subscale of the Stanford Time Perspective Inventory,23 the Life Outcome Expectancies Scale, and the Illness Cognition Questionnaire (ICQ).24 The Future Orientation subscale23 was used to assess the degree to which participants were striving for future goals and rewards, to approximate the qualitatively described resilience process “re-evaluating life goals.” The Life Outcome Expectancies measure was designed specifically for ATN 070 and consists of questions measuring participants' perceived control over their life circumstances and perceived likelihood of reaching life milestones. We used this scale to measure “gaining a sense of control.” The ICQ24 contains 18 items rated on a 4-point scale regarding their attitudes toward living with a chronic disease. We used this scale to approximate the cognitive resilience process “taking responsibility for health outcomes.” When all of these dimensions of cognitive resilience were combined into a single outcome measure, it displayed excellent reliability (α = 0.86).

We assessed behavioral resilience using a series of questions that asked: “What types of changes have you made in your lifestyle since learning you were HIV+?” Participants could answer “Yes,” “No,” or “I don't know” to a list of 17 items. This list of questions aligned with the three dimensions of behavioral resilience described in the qualitative study,8 including 11 items that corresponded to “Enacting healthy behavioral practices” (e.g., “Quit smoking,” “Increased exercise”), 5 items that corresponded to “Enlisting social support” (e.g., “Joined support group”), and 1 item that was potentially related to “Empowering other gay/bisexual youth” (“Educated others about HIV”). The sum of “Yes” answers to the 17 questions formed the behavioral resilience outcome utilized in the subsequent analyses (α = 0.82).

Demographics and covariates

Demographic variables included in this analysis were race, age, housing status, education, employment, and time since HIV diagnosis. We focused our selection of additional covariates on hypothesized promotive factors relating to identity and social support, as these have been demonstrated to be theoretically and/or empirically related to resilience in other studies. These included scales measuring ethnic identity,25 internalized homonegativity,26 HIV stigma,27 and social support.28

Ethnic identity was assessed using Phinney's multigroup ethnic identity measure, which has been validated in numerous studies with diverse youth (α = 0.87 in our sample).25,29 Internalized homonegativity was assessed using Mayfield's 23-item Internalized Homonegativity Inventory (IHNI), which had excellent reliability as well (α = 0.92).26 Participants' attitudes toward their identity as young men living with HIV were assessed using the 13-item Negative Self-Image subscale of the HIV Stigma Scale (α = 0.90).27 Participants' satisfaction with the quality and availability of their social support was assessed using the Emotional Support subscale of the Social Support for Adolescents Scale (α = 0.70).28

Data analysis

Descriptive analyses were performed for all variables. We examined distributions and associations between hypothesized promotive factors, demographics, and resilience outcome variables. Univariate analyses included frequencies and measures of central tendency and variability (Table 2). We conducted t-tests, one-way ANOVA, or simple linear regressions to assess bivariate relationships between predictors and resilience outcome variables (Tables 3 and 4). We created a correlation matrix to assess for multicollinearity between predictor variables (data not shown). Associations that were significant at P < 0.10 were retained in the multivariate models, as were the background demographic variables. Multivariate models were constructed using forward stepwise linear regression; demographic variables were included regardless of significance, however, the covariates were only retained in the model if they remained significant and improved the model. Separate multivariate regression models were developed for cognitive and behavioral resilience. All data analysis was conducted using SPSS statistical software (IBM Corp., Armonk, NY).

Table 2.

Characteristics of the Sample (n = 200)

  Mean (SD) Range
Age in years 21.15 (1.91) 16–24
Time since diagnosis (years) 2.40 (1.70) 0.07–8.14
  N (%)
Race/ethnicity
 Black/African American (not Latino) 132 (66.0)
 Hispanic/Latino 37 (18.5)
 White/Caucasian 14 (7.0)
 Multiracial/Biracial 10 (5.0)
 Asian/Pacific Islander 1 (0.5)
 Native American/Alaskan Native 2 (1.0)
 Other 4 (2.0)
Sexual orientation identity
 Gay/queer 156 (78.0)
 Bisexual 24 (12.0)
 Straight 3 (1.5)
 Trade 5 (2.5)
 Down low 3 (1.5)
 Questioning 2 (1.0)
 Other 7 (3.5)
Education
 Did not complete high school 53 (26.5)
 High school graduate 74 (37.0)
 Some college/technical school 73 (36.5)
Employment
 Full-time 44 (22.0)
 Part-time 47 (23.5)
 Not employed 109 (54.5)
Housing arrangement
 Own house/apartment 66 (33.0)
 Parent's house/apartment 70 (35.0)
 Family member(s) house/apartment 17 (8.5)
 Another person's house/apartment 18 (9.0)
 Foster/group home 3 (1.5)
 Boarding home/shelter/halfway 17 (8.5)
 Other 9 (4.5)

Table 3.

Bivariate Linear Regression Analysis of Variables Potentially Associated with Cognitive Resilience Among Y-GBMSM

Variable Coefficient (B) SE Beta P
Race (Black) 0.015 0.102 0.010 0.886
Age −0.816 0.704 −0.082 0.248
Education 5.487 1.666 0.228 0.001
Housing −3.416 1.486 −0.163 0.021
Employment 4.318 1.600 0.188 0.008
Time since diagnosis −0.105 0.759 −0.010 0.890
Internalized homonegativity −0.405 0.084 −0.325 <0.001
Ethnic identity 9.653 2.456 0.269 <0.001
HIV stigma −0.833 0.117 −0.451 <0.001
Social support satisfaction 2.309 0.328 0.447 <0.001
Behavioral resilience 1.439 0.351 0.280 <0.001

Table 4.

Bivariate Linear Regression Analysis of Variables Potentially Associated with Behavioral Resilience Among Y-GBMSM

Variable Coefficient (B) SE Beta P
Race (Black) −0.009 0.020 −0.033 0.641
Age −0.175 0.137 −0.090 0.204
Education −0.284 0.332 −0.061 0.394
Housing −0.251 0.289 −0.061 0.387
Employment −0.150 0.317 −0.034 0.637
Time since diagnosis −0.165 0.156 −0.076 0.292
Internalized homonegativity −0.004 0.017 −0.016 0.821
Ethnic identity 1.330 0.487 0.190 0.007
HIV stigma −0.029 0.025 −0.080 0.260
Social support satisfaction 0.260 0.069 0.259 <0.001
Cognitive resilience 0.055 0.013 0.280 <0.001

Results

Demographics

Two hundred Y-GBMSM participated in this study. Demographic characteristics are presented in Table 2. The majority of our participants identified as Black/African American, most identified as gay, most had completed high school, and approximately half were employed. The majority reported stable housing, either independently or with family members. The mean age of our sample was 21 years, and Y-GBMSM were diagnosed with HIV an average of 2.4 years before participation.

Bivariate analyses

In bivariate analyses, education, housing, employment, internalized homonegativity, ethnic identity, HIV stigma, social support satisfaction, and behavioral resilience were all significantly associated with cognitive resilience (Table 3). Ethnic identity, social support satisfaction, and cognitive resilience were significantly associated with behavioral resilience (Table 4).

Regression analyses

Stepwise multiple linear regressions were used to examine the relationship between the demographic/psychosocial predictor variables and the two types of resilience. Variables that were significantly associated with each outcome in the bivariate analyses were entered into the model using a forward stepwise elimination procedure to examine their relationship to the dependent variables. Multivariate regression analyses are presented in Tables 5 and 6.

Table 5.

Stepwise Regression Analysis Summary for Full Model Variables Predicting Cognitive Resilience

Variable B SEB Beta Delta R2
Less than high school education −6.452 2.397 −0.160**
HIV stigma −0.589 0.107 −0.339*** 0.214
Social support satisfaction 1.061 0.302 0.211** 0.095
Behavioral resilience 0.940 0.278 0.194** 0.037
Ethnic identity 5.898 2.022 0.173** 0.022
Internalized homonegativity −0.187 0.071 −0.160** 0.019

R2 = 0.678 (P < 0.001).

**

P < 0.01;***P < 0.001.

Table 6.

Stepwise Regression Analysis Summary for Full Model Variables Predicting Behavioral Resilience

Variable B SEB Beta Delta R2
Cognitive resilience 0.052 0.016 0.254** 0.097
Social support satisfaction 0.189 0.078 0.182* 0.023

R2 = 0.141 (P < 0.001).

*

P < 0.05;**P < 0.01.

Level of education, HIV-related stigma, social support satisfaction, behavioral resilience, ethnic identity, and internalized homonegativity were all significant predictors of cognitive resilience. The final model accounted for a substantial percentage of the overall variance (R2 = 0.678, P < 0.001). For behavioral resilience, the two predictors that remained in the final model were social support satisfaction and cognitive resilience. This model accounted for a smaller proportion of the variance in this outcome, but remained highly significant (R2 = 0.141, P < 0.001).

Discussion

Y-GBMSM living with HIV face multiple social stressors and intersecting stigmas; despite this, resilience with resultant positive health outcomes is often observed. In the current study, our aim was to examine factors associated with such resilience to inform future interventions in this key population.

We found that several psychosocial and demographic factors were significantly associated with cognitive resilience: level of education, HIV stigma, social support satisfaction, behavioral resilience, ethnic identity, and internalized homonegativity. In terms of Fergus and Zimmerman's framework,13 these primarily represent assets, resilience factors that lie within the individual. The associations with HIV stigma, ethnic identity, and internalized homonegativity highlight the importance of positive identity beliefs among these young men. The association between a positive view of one's ethnic identity and resilience has been similarly demonstrated in other studies of Black and Latino youth.30–33 In these studies, positive ethnic identity acted as a buffer between adverse circumstances and health outcomes. Prior research has also demonstrated that positive views of gay identity can be protective among gay youth and are often associated with favorable health outcomes despite concomitant stresses.34,35 In addition to these assets, social support satisfaction emerged as a significant predictor in our model and is a well-described resilience resource in adolescence and young adulthood.16 This has also been shown in studies focused on sexual and ethnic minority youth and their communities.36–38

When we examined associations with behavioral resilience, only two factors emerged as significant predictors: cognitive resilience and satisfaction with social support. The relationship between cognitive and behavioral resilience is consistent with the framework outlined in the preceding qualitative study (Fig. 1),8 in which the behavioral resilience processes seemed to represent an evolution from the cognitive resilience processes as participants acclimated to their HIV diagnosis.

Our findings about associations between identity constructs, social support, and resilience are consistent with previous literature.17–19 However, a somewhat unique feature of this analysis was that we focused on resilience dimensions themselves as our outcomes, as opposed to other resilience research that infers resilience based on positive physical or mental health outcomes as markers of resilience; while both approaches are important, our approach may help to shed more light on the mechanisms behind these favorable trajectories.39,40 Our study is also unique in that it explores resilience among Y-GBMSM living with HIV, a group among whom the bulk of the existing research focuses on risk.

Implications

Our findings have significant implications for the field, as there is an urgent need to develop interventions to support the health and well-being of Y-GBMSM, given their HIV burden. Currently, few evidence-based interventions exist specifically for Y-GBMSM living with HIV. Furthermore, those behavioral interventions that do exist focus mainly on decreasing the risk of secondary transmission. Our findings could inform more holistic interventions that aim to improve generalized coping mechanisms and well-being in this population. The associations between positive identity development and cognitive resilience suggest that programs which aim to strengthen cultural awareness and pride, with respect to race/ethnicity, gay/bisexual identity, and HIV-positive identity, could help to promote resilience among these young men. Certain programs like this have already been developed for HIV prevention purposes, such as the Many Men, Many Voices intervention for Black GBMSM, and could potentially be modified for youth already living with HIV.41 The prominence of social support satisfaction, as a predictor of both behavioral and cognitive dimensions of resilience, suggests that there may also be a particularly useful role for group-based interventions or those that involve peers or other support persons from Y-GBMSM social networks. Finally, given the association between education level and cognitive dimensions of resilience, initiatives to promote educational attainment may also be helpful for building resilience among Y-GBMSM living with HIV.

Strengths and limitations

Our study examined cognitive and behavioral dimensions of resilience using quantitative methods, which build on and correspond well with previous qualitative findings from our parent study.8 This mixed methods approach adds to the extant literature by confirming findings previously reported by Harper et al.8 In addition, we are contributing to the small but growing body of research in youth living with HIV that focuses on resilience as opposed to a pure risk paradigm.

However, there are limitations that warrant mention. This was a secondary data analysis that did not originally aim to measure resilience. That being said, our measures of cognitive and behavioral resilience were grounded in our prior qualitative work,8 theoretically similar to established measures of resilience,20–22 and demonstrated good reliability. Future work could build on these preliminary findings to further refine these measures, so that they could be used again in future studies of youth living with HIV.

Our measurements of resilience dimensions were dependent on self-report, and the behavioral dimensions in particular might be vulnerable to social desirability and recall biases (e.g., participants might report stopping smoking). Future studies could aim to incorporate biologic health outcomes (e.g., HIV viral load) to depict health behaviors more accurately. It is also important to note that resilience is not theorized to be a static characteristic, but rather made up of dynamic processes that change with time and context.13 Given this, a more ideal study of resilience would be longitudinal; the cross-sectional nature of this analysis is a limitation that we hope can be addressed in future work.

Finally, our patients were recruited from clinical care settings for youth living with HIV and, therefore, had the resourcefulness and motivation to test for HIV and seek healthcare. It is estimated that over 50% of youth living with HIV are unaware of their status, and many youth who are living with HIV are not linked to care.42 Our participants may, therefore, represent a more resilient population relative to Y-GBMSM overall, even though wide variability was still seen in our group.

Conclusions

Our study highlights the importance of both cognitive and behavioral dimensions of resilience among Y-GBMSM living with HIV, an area that is understudied in the literature. Our findings highlighted identity development, education, and social support satisfaction as key psychosocial factors that were closely related to resilience. Future intervention development should focus on these promotive factors to more effectively support health and well-being in this population. Ultimately, this line of research can inform positive, resilience-based efforts to optimize healthcare outcomes among Y-GBMSM living with HIV.

Contributor Information

Collaborators: on behalf of the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN)

Acknowledgments

The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) is funded by grants 5 U01 HD 40533 and 5 U01 HD 40474 from the National Institutes of Health through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (Bill Kapogiannis, MD; Sonia Lee, PhD) with supplemental funding from the National Institute on Drug Abuse (Nicolette Borek, PhD) and National Institute of Mental Health (Susannah Allison, PhD; Pim Brouwers, PhD). We acknowledge the contribution of the investigators and staff at the following ATN sites who participated in this study: University of South Florida, Tampa (Emmanuel, Rebolledo, Callejas), Children's Hospital of Los Angeles (Belzer, Flores, Tucker), Children's National Medical Center (D'Angelo, Hagler, Trexler), Children's Hospital of Philadelphia (Douglas, Tanney, DiBenedetto), John H. Stroger Jr. Hospital of Cook County and the Ruth M. Rothstein CORE Center (Martinez, Bojan, Jackson), University of Puerto Rico (Febo, Ayala-Flores, Fuentes-Gomez), Montefiore Medical Center (Futterman, Enriquez-Bruce, Campos), Mount Sinai Medical Center (Steever, Geiger), University of California-San Francisco (Moscicki, Molaghan, Irish), Tulane University Health Sciences Center (Abdalian, Kozina, Baker), University of Maryland (Peralta, Flores, Gorle), University of Miami School of Medicine (Friedman, Maturo, Major-Wilson), Children's Diagnostic and Treatment Center (Puga, Leonard, Inman), St. Jude's Children's Research Hospital (Flynn, Dillard), and Children's Memorial Hospital (Garofalo, Cagwin, Brennan). The authors acknowledge the input and support of the ATN Coordinating Center for Network scientific and logistical support (Craig Wilson, MD; Cynthia Partlow, MEd); the ATN Data and Operations Center at Westat (Jim Korelitz, PhD; Barbara Driver, RN, MS); the ATN Community Advisory Board; and the youth who participated in the study.

Disclaimer

Parts of this work were presented previously at the national meeting of the Adolescent Trials Network in Bethesda, Maryland, October 5, 2015.

Author Disclosure Statement

No competing financial interests exist.

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