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(A) Tumor volumes ranked from large to small: blank group, WP1130 group, cisplatin group, and co-treatment group. (B) The body weights of the mice were not significantly different following treatment. (C) Compared with the control, treatment with cisplatin or WP1130 alone delayed tumor growth and decreased tumor size and weight. (D) Tumor regression rate in the co-treatment group was significantly higher compared to that in the single-reagent groups.
