Table 2. Levels of ESM-1 in MPE and association with the clinicopathological factors of NSCLC patients.

Clinical variables	Number	ESM-1(ng/ml)	P-value
Age (years)			0.563
≥ 65	23	54.93 ± 8.12
< 65	47	49.33 ± 5.46
Gender			0.930
Male	40	50.82 ± 5.53
Female	30	51.63 ± 7.61
Histological type			0.756
Adenocarcinoma	53	51.97 ± 5.36
Squamous cell carcinoma	17	48.6 7 ± 8.30
Performance Status			0.515
0 to 1	35	48.20 ± 6.20
2 to 4	35	54.14 ± 6.59
Smoking status			0.138
Nonsmoker	36	44.65 ± 6.00
Smoker	34	58.07 ± 6.65
Tumor size (cm)			0.218
≤ 5	41	46.47 ± 5.17
> 5	29	57.82 ± 8.01
Distant metastasis			0.020a
Absent	31	39.18 ± 5.34
Present	39	60.16 ± 6.49

^aSignificant difference.