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. 2017 May 17;8(30):49702–49712. doi: 10.18632/oncotarget.17922

Table 2. Clinical and pathologic information.

N Expression of PD-L1(%) pa
Negative Positive
Total 64 14 (21.88) 50 (78.12)
Gender 0.183
Male 33 5 (15.15) 28 (84.85)
Female 31 9 (29.03) 22 (70.97)
Age 0.580
< 60 45 9 (20.00) 36 (80.00)
≥ 60 19 5 (26.32) 14 (73.68)
KPS 0.080
< 80 9 4 (44.44) 5 (55.56)
≥ 80 55 10 (18.18) 45 (81.82)
WHO Grade 0.013
LGG 23 9 (39.13) 14 (60.87)
PA 11 5 6
DA 12 4 8
HGG 41 5 (12.20) 36 (87.80)
AA 13 1 12
GBM 28 4 24
VEGF 0.002
Negative 10 6 (60.00) 4 (40.00)
Positive 54 8 (14.81) 46 (85.19)
MMP-9 0.068
Negative 12 5 (41.67) 7 (58.33)
Positive 52 9 (17.31) 43 (82.69)
Ki-67 0.002
Negative 13 7 (53.85) 6 (46.15)
Positive 51 7 (13.73) 44 (86.27)

aThe correlation between PD-L1 expression and clinicopathological features was assessed by Mann–Whitney U test. Abbreviations: LGG, low grade glioma; PA, pilocytic astrocytoma; DA, diffuse astrocytoma; HGG, high grade glioma; AA, anaplastic astrocytoma; GBM, glioblastoma.