Table 1. Summary of the eight included studies.
Study | Origin of population | Study design | Disease | N | Stage | TUG1 assay | Survival analysis | Metastasis analysis | Hazard ratios | Follow-up Months |
---|---|---|---|---|---|---|---|---|---|---|
Zhang 2014 [13] | China | R | NSCLC | 192 | I/II, III/IV | qRT-PCR | OS | LNM | K-M | 60 |
Tan 2015 [14] | China | R | BC | 54 | I–IV | qRT-PCR | OS | NA | K-M | 60 |
Zhang 2016 [19] | China | R | GC | 100 | I/II, III/IV | qRT-PCR | OS | LNM/DM | K-M/HR | 60 |
Sun 2016 [18] | China | R | CC | 120 | NA | qRT-PCR | OS | LNM | K-M | 60 |
Ma 2016 [17] | China | R | OSA | 76 | I/II, III/IV | qRT-PCR | OS, PFS | IM | K-M/HR | 60 |
Jiang 2016 [15] | China | R | ESCC | 218 | I/II, III/IV | qRT-PCR | OS | LNM | K-M/HR | 80 |
Iliev 2016 [16] | Czech Republic | R | BC | 47 | I/II, III/IV | qRT-PCR | OS | DM | K-M | 150 |
Niu 2017 [20] | China | R | SCLC | 33 | NA | qRT-PCR | OS | NA | K-M | 30 |
Study design is described as retrospective (R); OSA, osteosarcoma; GC, gastric cancer; BC, bladder cancer; CC, colorectal cancer; SCLC, small cell lung cancer; NSCLC, Non small cell lung cancer; ESCC, esophageal squamous cell carcinoma; DM, distant Metastasis; LNM, Lymph Node Metastasis; IM, Initial metastasis