Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of BifR-mediated gene regulation. BifR (purple) exists as a dimer under reducing conditions. Two BifR dimers bind adjacent palindromes. Upon oxidation, a disulfide bond links two BifR dimers; in this condition, repression of gene activity is more efficient, perhaps because RNA polymerase fails to displace promoter-bound BifR.
