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. 1984 Mar;3(3):603–610. doi: 10.1002/j.1460-2075.1984.tb01855.x

Rearrangements of the transposable mating-type cassettes of fission yeast.

D H Beach, A J Klar
PMCID: PMC557395  PMID: 6325178

Abstract

The fission yeast, Schizosaccharomyces pombe, switches mating type every few cell divisions. Switching is controlled by the genes of the mating-type locus, which consists of three components, mat1, mat2-P and mat3-M, each separated by approximately 15 kb. Copy transposition of P (Plus) or M (Minus) information from mat2-P or mat3-M into the expression locus mat1 mediates cell type switching. The mating-type locus undergoes events at high frequency (10(-2)-10(-6)) which stabilize one or other mating type. These events are shown to be rearrangements which result in either deletion or insertion of DNA between cassettes.

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Selected References

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