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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Bioessays. 2017 Aug 9;39(9):10.1002/bies.201700073. doi: 10.1002/bies.201700073

Figure 5.

Figure 5

Model of Blm in Drosophila meiotic recombination. A: After D-loop formation, Blm can unwind intermediate that have undergone synthesis to create a noncrossover, or if no synthesis occurred, Blm can unwind to regenerate the 3′ resected end intermediate. B: Crossover-designated D-loop intermediates are processed through the Class I pathway to be resolved into patterned crossovers. C: Alternatively, D-loop intermediates can be processed by the Class II pathway to generate both crossovers and noncrossovers.