Table 4. Association of beclin 1 expression with patients’ clinicopathologic features in 105 patients with ER-positive breast cancer.
| Variable | Beclin 1 expression | |||
|---|---|---|---|---|
| All Cases | Low | High | p Value* | |
| Age at surgery (years) | 0.780 | |||
| <=53(mean age) | 60 | 49(79.0%) | 13(21.0%) | |
| >53 | 45 | 33(76.7%) | 10(23.3%) | |
| Histological grade | 0.179 | |||
| G1 | 23 | 19(82.6%) | 4(17.4%) | |
| G2 | 74 | 59(79.7%) | 15(20.3) | |
| G3 | 8 | 4(50.0%) | 4(50.0%) | |
| Tumor size | 0.408 | |||
| <=5cm | 99 | 76(76.8%) | 23(23.2%) | |
| >5cm | 6 | 6(100.0%) | 0(0%) | |
| Lymph node metastasis | 0.757 | |||
| negative | 40 | 32(80.0%) | 8(20.0%) | |
| positive | 62 | 48(77.4%) | 14(22.6%) | |
| AJCC | 0.500 | |||
| I | 8 | 7(87.5%) | 1(12.5%) | |
| II | 62 | 50(80.6%) | 12(19.4%) | |
| III | 32 | 23(71.9%) | 9(28.1%) | |
| IV | 0 | — | — | |
| HER2 expression | <0.001* | |||
| Negative | 86 | 76(88.4%) | 10(11.6%) | |
| Positive | 19 | 6(31.6%) | 13(68.4%) | |