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. Author manuscript; available in PMC: 2018 May 25.
Published in final edited form as: Oncogene. 2016 Dec 19;36(21):3015–3024. doi: 10.1038/onc.2016.455

Figure 4. PAX2 re-expression in human HGSC cell lines reduces proliferation and migration via increased apoptosis.

Figure 4

PAX2 transient expression in PAX2-null serous cancer cell lines resulted in significant reduction in A) proliferation (day 3) and B) migration (hour 8). C) PAX2 expression in OVCAR4 cells significantly increased early and late apoptosis compared to OVCAR4 cells treated with NEO (measured by flow cytometry) at hour 48.