Table 4. Results of sensitivity analysis of meta-analysis for ADPIOQ rs1501299 polymorphisms and CAD in type 2 diabetic patients.
T VS G | TT+TG VS GG | TT VS TG+GG | GT VS GG | TT VS GG | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Study group 2 | OR[95%CI] | I2(%)/Ph | OR[95%CI] | I2/Ph | OR[95%CI] | I2/Ph | OR[95%CI] | I2/Ph | OR[95%CI] | I2/Ph |
Total | 0.91[0.78,1.07] | 64/0.003 | 0.95[0.78,1.16] | 63/0.004 | 0.40[0.22,0.71] | 84/0.000 | 1.00[0.82,1.21] | 56/0.020 | 0.67[0.54,0.83] | 36/0.120 |
Mohammadzadeh2016 | 0.86[0.76,0.98] | 46/0.06 | 0.89[0.75,1.05] | 49/0.05 | 0.34[0.19,0.60] | 84/0.000 | 0.95[0.79,1.13] | 45/0.070 | & | & |
Katakami2012 | 0.94[0.79,1.12] | 64/0.04 | 0.99[0.80,1.23] | 61/0.009 | 0.39[0.21,0.73] | 86/0.000 | 1.05[0.86,1.27] | 50/0.040 | & | & |
Esteghamati2012 | 0.94[0.81,1.10] | 59/0.01 | 0.99[0.82,1.20] | 58/0.02 | 0.47[0.33,0.67] | 49/0.050 | 1.04[0.86,1.25] | 50/0.040 | & | & |
Al-Daghri2011 | 0.90[0.76,1.07] | 67/0.002 | 0.95[0.76,1.18] | 67/0.002 | 0.39[0.20,0.74] | 86/0.000 | 1.00[0.81,1.24] | 61/0.009 | & | & |
Chiodini2010 | 0.94[0.79,1.12] | 63/0.006 | 0.98[0.78,1.23] | 64/0.005 | 0.37[0.20,0.71] | 83/0.000 | 1.03[0.82,1.28] | 58/0.010 | & | & |
Qi2006 | 0.92[0.76,1.10] | 68/0.002 | 0.96[0.76,1.21] | 67/0.002 | 0.41[0.21,0.79] | 86/0.000 | 1.01[0.81,1.26] | 61/0.009 | & | & |
Qi2005 | 0.90[0.76,1.08] | 66/0.003 | 0.93[0.74,1.15] | 63/0.005 | 0.42[0.22,0.81] | 86/0.000 | 0.97[0.79,1.19] | 54/0.020 | & | & |
Lacquemant Swiss2004 | 0.91[0.77,1.08] | 68/0.002 | 0.95[0.76,1.17] | 67/0.002 | 0.38[0.21,0.72] | 86/0.000 | 1.00[0.81,1.23] | 61/0.009 | & | & |
Lacquemant French2004 | 0.89[0.76,1.04] | 63/0.006 | 0.94[0.76,1.17] | 66/0.002 | 0.38[0.21,0.71] | 86/0.000 | 0.97[0.80,1.18] | 57/0.020 | & | & |
Bacci2004 | 0.92[0.77,1.09] | 68/0.002 | 0.92[0.75,1.12] | 63/0.006 | 0.42[0.22,0.78] | 86/0.000 | 0.97[0.79,1.20] | 58/0.010 | & | & |
Abbreviations: Ph, P value for heterogeneity from Q-test; I2, the proportion of the total variation across studies due to heterogeneity; CI, confidence interval; OR, odds ratio.
&No heterogeneity was observed in the homozygote model.
Significant results are marked in bold.