MICROBIOLOGY. For the article “Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis” by Laurent Coscoy and Don Ganem, which appeared in number 14, July 5, 2000, of Proc. Natl. Acad. Sci. USA (97, 8051–8056; First Published June 20, 2000; 10.1073/pnas.140129797), the authors note that in Fig. 3A, images of the identical gel were inadvertently reproduced twice, once in the control row and once in the experimental row. The error occurred during figure preparation and reflects the fact that in both the control and the experimental cell lines, MHC-I chains are processed identically, generating images that are very similar. The corrected Fig. 3A and its legend are printed below. No conclusions of the paper are affected.
Figure 3.
Intracellular transport and stability of MHC I molecules. (A) HeLa cells stably transfected with pCEP4-K3 (Right) or the pCEP4 vector alone (Left) were metabolically labeled for 20 min and chased for the indicated time periods. After being lysed in 1% Nonidet P-40, lysates were divided into three aliquots. Two were kept on ice and one was incubated at 37°C for 1 h. Heterodimeric MHC I molecules were immunoprecipitated with mAb W6/32 and treated with endo H where indicated.