Table 3. Basic information of candidate SNPs in this study.
SNP | Chr | Gene | allel | MAF(case) | MAF(control) | HWE | OR | 95%CI | P | |
---|---|---|---|---|---|---|---|---|---|---|
rs3783550 | 2q13 | IL1A | T/G | 0.38 | 0.33 | 0.399 | 1.28 | 1.04 | 1.58 | 0.018* |
rs3783546 | 2q13 | IL1A | C/G | 0.38 | 0.33 | 0.459 | 1.30 | 1.05 | 1.60 | 0.014* |
rs2856838 | 2q13 | IL1A | A/G | 0.27 | 0.25 | 0.320 | 1.12 | 0.89 | 1.40 | 0.338 |
rs1609682 | 2q13 | IL1A | T/G | 0.38 | 0.33 | 0.398 | 1.29 | 1.05 | 1.59 | 0.016* |
rs3783521 | 2q13 | IL1A | G/A | 0.38 | 0.33 | 0.399 | 1.29 | 1.05 | 1.59 | 0.015* |
rs2853550 | 2q13 | IL1B | A/G | 0.11 | 0.09 | 0.067 | 1.29 | 0.92 | 1.79 | 0.137 |
rs1143643 | 2q13 | IL1B | C/T | 0.48 | 0.47 | 0.191 | 1.01 | 0.83 | 1.23 | 0.926 |
rs3136558 | 2q13 | IL1B | G/A | 0.41 | 0.37 | 0.617 | 1.21 | 0.99 | 1.48 | 0.066 |
rs1143630 | 2q13 | IL1B | T/G | 0.18 | 0.16 | 1.000 | 1.16 | 0.89 | 1.51 | 0.262 |
rs1143627 | 2q13 | IL1B | G/A | 0.49 | 0.48 | 0.160 | 1.05 | 0.86 | 1.28 | 0.618 |
rs16944 | 2q13 | IL1B | A/G | 0.49 | 0.48 | 0.162 | 1.06 | 0.87 | 1.29 | 0.556 |
rs1143623 | 2q13 | IL1B | G/C | 0.41 | 0.40 | 0.286 | 1.04 | 0.85 | 1.28 | 0.675 |
rs17042888 | 2q13 | IL1RN | A/G | 0.27 | 0.26 | 0.470 | 1.05 | 0.84 | 1.31 | 0.697 |
rs928940 | 2q13 | IL1RN | T/G | 0.41 | 0.39 | 0.000 | 1.07 | 0.87 | 1.31 | 0.510 |
rs3181052 | 2q13 | IL1RN | G/A | 0.43 | 0.41 | 0.248 | 1.09 | 0.89 | 1.34 | 0.384 |
rs452204 | 2q13 | IL1RN | G/A | 0.36 | 0.35 | 1.000 | 1.06 | 0.86 | 1.30 | 0.594 |
*p value ≤ 0.05 indicates statistical significance; A/B stands for minor/major alleles on the control sample frequencies. HWE: Hardy–Weinberg equilibrium; MAF: minor allele frequency; OR: odds ratio; SNP: single-nucleotide polymorphisms.