Table 6. The association between SNPs and smoking, drinking status, age analysis of RCC patients.
| SNP | Allel | Smoking status | Drinking status | Age | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Smoking | Nosmoking | Drinking | Nodrinking | >55 | ≤55 | ||||||||
| OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | ||
| rs3783550 | T/G | 1.37(1.03-1.81) | 0.029 | 1.20(0.85-1.68) | 0.308 | 0.95(0.60-1.50) | 0.823 | 1.43(1.11-1.85) | 0.006 | 1.43(1.11-1.85) | 0.003 | 1.01(0.74-1.38) | 0.959 |
| rs3783546 | C/G | 1.39(1.05-1.84) | 0.019 | 1.20(0.85-1.68) | 0.308 | 0.95(0.60-1.51) | 0.836 | 1.45(1.13-1.87) | 0.004 | 1.45(1.13-1.87) | 0.003 | 1.03(0.76-1.41) | 0.831 |
| rs2856838 | A/G | 1.18(0.87-1.61) | 0.284 | 0.99(0.68-1.43) | 0.941 | 0.93(0.57-1.53) | 0.774 | 0.83(0.63-1.10) | 0.198 | 0.83(0.63-1.10) | 0.020 | 0.81(0.57-1.14) | 0.227 |
| rs1609682 | T/G | 1.38(1.04-1.82) | 0.023 | 1.20(0.85-1.68) | 0.308 | 0.95(0.60-1.50) | 0.823 | 1.44(1.12-1.85) | 0.005 | 1.44(1.12-1.85) | 0.003 | 1.03(0.75-1.41) | 0.845 |
| rs3783521 | G/A | 1.39(1.05-1.83) | 0.021 | 1.20(0.85-1.68) | 0.308 | 0.95(0.60-1.50) | 0.823 | 1.45(1.12-1.86) | 0.004 | 1.45(1.12-1.86) | 0.003 | 1.03(0.75-1.41) | 0.845 |
| rs2853550 | A/G | 1.43(0.93-2.21) | 0.106 | 1.17(0.66-2.06) | 0.591 | 0.80(0.36-1.80) | 0.589 | 1.49(0.99-2.23) | 0.052 | 1.49(0.99-2.23) | 0.142 | 1.26(0.78-2.03) | 0.340 |
| rs1143643 | C/T | 1.10(0.84-1.43) | 0.495 | 1.30(0.93-1.82) | 0.121 | 0.95(0.62-1.48) | 0.836 | 1.01(0.79-1.29) | 0.939 | 1.01(0.79-1.29) | 0.453 | 0.98(0.73-1.31) | 0.869 |
| rs3136558 | G/A | 1.38(1.05-1.82) | 0.020 | 0.94(0.67-1.32) | 0.708 | 1.11(0.71-1.74) | 0.644 | 1.20(0.93-1.53) | 0.157 | 1.20(0.93-1.53) | 0.817 | 1.36(1.01-1.84) | 0.044 |
| rs1143630 | T/G | 1.43(1.01-2.04) | 0.045 | 0.82(0.53-1.28) | 0.381 | 0.79(0.43-1.46) | 0.453 | 0.77(0.56-1.07) | 0.114 | 0.77(0.56-1.07) | 0.162 | 1.06(0.72-1.56) | 0.764 |
| rs1143627 | G/A | 1.03(0.78-1.34) | 0.851 | 1.10(0.79-1.54) | 0.568 | 0.95(0.61-1.47) | 0.814 | 1.03(0.81-1.32) | 0.803 | 1.03(0.81-1.32) | 0.414 | 0.98(0.73-1.32) | 0.915 |
| rs16944 | A/G | 1.03(0.79-1.35) | 0.803 | 1.11(0.79-1.54) | 0.548 | 0.96(0.62-1.48) | 0.847 | 1.04(0.82-1.33) | 0.738 | 1.04(0.82-1.33) | 0.291 | 0.97(0.72-1.30) | 0.834 |
| rs1143623 | G/C | 0.97(0.74-1.27) | 0.801 | 1.16(0.83-1.64) | 0.378 | 1.02(0.65-1.60) | 0.933 | 1.01(0.79-1.29) | 0.944 | 1.01(0.79-1.29) | 0.592 | 1.01(0.75-1.36) | 0.965 |
| rs17042888 | A/G | 0.82(0.60-1.11) | 0.194 | 1.34(0.92-1.95) | 0.129 | 0.89(0.53-1.49) | 0.663 | 1.02(0.77-1.34) | 0.915 | 1.02(0.77-1.34) | 0.974 | 1.00(0.72-1.40) | 0.996 |
| rs928940 | T/G | 0.89(0.68-1.18) | 0.429 | 1.20(0.86-1.69) | 0.287 | 0.95(0.61-1.49) | 0.824 | 1.03(0.80-1.32) | 0.831 | 1.03(0.80-1.32) | 0.528 | 1.14(0.84-1.54) | 0.406 |
| rs3181052 | G/A | 1.00(0.77-1.31) | 0.983 | 1.13(0.80-1.57) | 0.491 | 0.89(0.57-1.39) | 0.620 | 1.10(0.86-1.41) | 0.451 | 1.10(0.86-1.41) | 0.226 | 1.33(0.99-1.79) | 0.061 |
| rs452204 | G/A | 0.93(0.70-1.23) | 0.605 | 1.22(0.86-1.72) | 0.268 | 1.06(0.67-1.67) | 0.811 | 1.02(0.79-1.32) | 0.876 | 1.02(0.79-1.32) | 0.398 | 1.25(0.92-1.70) | 0.159 |