Table 1. GRP78 expression levels in bone marrow increased from MGUS to NDMM and RRMM.
Patients | GRP78 levels | |||
---|---|---|---|---|
median | [95% CI] | IQR | p-value | |
MGUS (n = 29) | 2.5 ng/mL | 1.7–6.4 | 1.6–8.4 | |
NDMM pts (n = 29) | 3.1 ng/mL | 1.8–7.3 | 1.7–11.4 | |
RRMM pts. (n = 15) | 4.0 ng/mL | 1.6–7.8 | 1.6–7.3 | |
All pts (73) | 3.3 ng/mL | 2.0–5.4 | 1.6–8.4 | p = 0.8 |
Abbrevations: MGUS, monoclonal gammopathy undetermined significance; MM, multiple myeloma; NDMM, newly diagnosed multiple myeloma; RRMM, relapsed refractory multiple myeloma; [95% CI], Confidence interval; IQR, Interquartile range.