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. 2017 May 25;8(34):56780–56790. doi: 10.18632/oncotarget.18187

Table 1. Characteristics of studies included in the meta-analysis.

Author last name Year Cancer type Country Ethnicity Design Genotype method Case Control MAF HWE Score
II ID DD All II ID DD All
Sun 2007 Lung China Asian PB PCR-RFLP 756 348 45 1149 640 407 64 1111 0.24 0.947 11
Sun 2007 Esophagus China Asian PB PCR-RFLP 652 328 38 1018 543 338 56 937 0.24 0.724 11
Sun 2007 Gastric China Asian PB PCR-RFLP 262 142 16 420 233 152 25 410 0.25 0.975 11
Sun 2007 Colorectal China Asian PB PCR-RFLP 605 280 33 918 528 304 58 890 0.24 0.116 11
Sun 2007 Breast China Asian PB PCR-RFLP 699 371 49 1119 513 419 72 1004 0.28 0.279 11
Sun 2007 Cervical China Asian PB PCR-RFLP 199 102 13 314 314 211 42 567 0.26 0.428 10
Yang 2008 Pancreatic China Asian PB PCR-RFLP 268 111 18 397 521 323 63 907 0.25 0.185 13
Pittman 2008 Colorectal England Caucasian PB AS-PCR 995 1897 987 3879 892 1872 897 3661 0.50 0.170 9
Frank 2008 Breast Germany Caucasian HB Fluorescent 298 535 221 1054 270 506 263 1039 0.50 0.403 7
Frank 2008 Breast England Caucasian PB Fluorescent 235 541 251 1027 245 608 321 1174 0.53 0.169 10
Frank 2008 Breast Germany Caucasian PB Fluorescent 280 509 222 1011 285 492 229 1006 0.47 0.550 9
Frank 2008 Breast England Caucasian PB Fluorescent 1133 2115 1050 4298 1149 2263 1062 4474 0.49 0.422 8
Cybulski 2008 Breast Poland Caucasian PB AS-PCR 178 314 126 618 274 499 192 965 0.46 0.195 6
Cybulski 2008 Prostate Poland Caucasian PB AS-PCR 139 236 110 485 274 499 192 965 0.46 0.195 6
Li 2008 Melanoma USA Caucasian HB PCR 243 385 177 805 207 440 188 835 0.49 0.116 11
Wang 2009 Bladder China Asian HB PCR-RFLP 238 115 12 365 205 138 25 368 0.26 0.786 10
Gangwar 2009 Bladder India Asian HB PCR-RFLP 121 84 7 212 133 101 16 250 0.27 0.584 9
De Vecchi 2009 Breast Italy Caucasian PB PCR-RFLP 162 301 117 580 106 206 94 406 0.49 0.752 7
Zhu 2010 RCC China Asian HB PCR-RFLP 226 119 8 353 205 139 21 365 0.25 0.686 11
Srivastava 2010 Gallbladder India Asian PB PCR-RFLP 147 69 12 228 122 84 24 230 0.29 0.103 11
Liu 2010 Colorectal China Asian PB PCR-RFLP 233 116 21 370 528 278 32 838 0.20 0.538 13
Li 2010 HNSCC USA Caucasian HB PCR–RFLP 311 456 256 1023 257 542 253 1052 0.50 0.324 10
Xiao 2011 Lymphoma China Asian NM PCR-PAGE 43 17 4 64 89 38 6 133 0.19 0.460 3
Xiao 2011 Lymphoma China Asian NM PCR-PAGE 49 23 3 75 63 40 4 107 0.22 0.442 3
Umar 2011 Esophageal India Asian PB PCR 139 103 17 259 138 93 28 259 0.29 0.046 11
Theodoropoulos 2011 Colorectal Greece Caucasian HB RFLP-PCR 103 201 98 402 120 254 106 480 0.49 0.194 9
Malik 2011 Esophageal India Asian HB RFLP-PCR 68 59 8 135 96 75 24 195 0.32 0.127 8
Malik 2011 Gastric India Asian HB RFLP-PCR 59 44 5 108 96 75 24 195 0.32 0.127 8
Ma 2011 Ovarian China Asian HB MassARRAY 128 87 3 218 138 122 25 285 0.30 0.789 8
Liamarkopoulos 2011 Gastric Greece Caucasian HB PCR-RFLP 35 42 11 88 120 254 106 480 0.49 0.194 7
Hart 2011 Lung Norway Caucasian PB TaqMan 125 210 101 436 106 209 118 433 0.51 0.481 10
Chatterjee 2011 Cervical South Africa African HB PCR-RFLP 18 63 25 106 43 129 85 257 0.58 0.614 6
Fu 2011 Prostate China Asian HB PCR-RFLP 257 132 17 406 211 159 38 408 0.29 0.315 10
Wang 2012 RCC China Asian HB PCR-RFLP 192 101 7 300 168 114 18 300 0.25 0.817 10
Wang 2012 PTC China Asian HB PCR–RFLP 65 45 8 118 106 92 15 213 0.29 0.408 7
Tong 2012 ALL China Asian HB PCR-RFLP 217 113 31 361 338 153 28 519 0.20 0.057 10
Hashemi 2012 Breast Iran Asian HB AS-PCR 113 107 16 236 79 91 33 203 0.39 0.434 6
George 2012 Prostate India Asian HB PCR-RFLP 84 69 12 165 116 83 6 205 0.23 0.050 9
Xiao 2013 Colorectal China Asian HB PCR-PAGE 187 107 11 305 212 115 15 342 0.21 0.905 7
Wu 2013 Colorectal China Asian HB PCR-SSCP 284 152 15 451 358 244 29 631 0.24 0.119 11
De Martino 2013 RCC Austria Caucasian HB PCR-RFLP 72 138 40 250 53 129 68 250 0.53 0.572 9
Pardini 2014 Colorectal Spain Caucasian PB Taqman 500 996 482 1978 425 802 420 1647 0.50 0.290 11
Pardini 2014 Colorectal Italy Caucasian PB Taqman 195 285 137 617 783 1230 538 2551 0.45 0.178 9
Pardini 2014 Colorectal USA Caucasian PB Taqman 237 514 259 1010 383 794 403 1580 0.51 0.835 9
Pardini 2014 Colorectal England Caucasian PB Taqman 410 825 341 1576 165 393 209 767 0.53 0.436 11
Pardini 2014 Colorectal Czech Caucasian PB Taqman 239 479 249 967 169 326 177 672 0.51 0.443 10
Pardini 2014 Colorectal Netherlands Caucasian PB Taqman 169 282 134 585 106 177 76 359 0.46 0.895 8
Tang 2015 OSCC China Asian HB PCR-RFLP 328 159 18 505 276 197 34 507 0.26 0.885 10
Carvalho 2015 ALL Brazil Mixed NM PCR 23 81 26 130 47 53 25 125 0.41 0.163 4

MAF: minor allele frequency; HWE: Hardy-Weinberg equilibrium; OSCC: oral squamous cell carcinoma; PTC: papillary thyroid carcinoma; RCC: renal cell carcinoma; HNSCC: head and neck squamous cell carcinoma; ALL: acute lymphocytic leukemia; PB: population based; HB: hospital based; NM: not mentioned; PCR-PAGE: polymerase chain reaction-polyacrylamide gel electrophoresis; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism; AS-PCR: allele-specific polymerase chain reaction.