Table 1. Sensitivity, specificity, positive predictive value and negative predictive value of 4 methods in the diagnosis of TBM.

Group	TBM group (n = 172)	non-TBM group (n = 28)	Sensitivity (%)	specificity (%)	positive predictive value (%)	negative predictive value (%)	median time to final diagnosis
LAMP positive	74	2	43.02	92.86	97.37	20.97	1h
LAMP negative	98	26	——	——	——	——	——
RTFQ PCR positive	59	0	34.30	100	100	19.86	4h
RTFQ PCR negative	113	28	——	——	——	——	——
Acid-fast staining positive	5	0	2.91%	100	100	14.36	1d
Acid-fast staining negative	167	28	——	——	——	——	——
MGIT960 culture positive	22	0	12.79	100	100	15.73	41d
MGIT960 culture negative	150	28	——	——	——	——	——