Biochemistry. In the article “Requirement of G_M2 ganglioside activator for phospholipase D activation” by Shun-ichi Nakamura, Toshihiro Akisue, Hitoshi Jinnai, Tomohiro Hitomi, Sukumar Sakar, Noriko Miwa, Taro Okada, Kimihisa Yoshida, Shun’ichi Kuroda, Ushio Kikkawa, and Yasutomi Nishizuka, which appeared in number 21, October 13, 1998, of Proc. Natl. Acad. Sci. USA (95, 12249–12253), the authors would like to note that the position of Figs. 3 and 4 were transposed. The correct figures and their legends are reproduced below.

Figure 3.

Enhancement by PLD activator of enzymatic conversion of G_M2 to G_M3 ganglioside catalyzed by β-hexosaminidase A. Purified PLD activator was loaded on a Superdex 200 column (Fig. 1). Each fraction was assayed for the ability to stimulate enzymatic conversion of G_M2 to G_M3 ganglioside catalyzed by β-hexosaminidase A. PLD activation also is plotted in the same figure. •, PLD activity; ○, G_M3 formation.

Figure 4.

Stimulation of PLD by G_M2 ganglioside activator or heat-stable PLD activator. (A) Stimulation of PLD by various amounts of purified G_M2 ganglioside activator or by heat-stable PLD activator. • and ○, with G_M2 ganglioside activator; ■ and □, with heat-stable PLD activator; • and ■, with 200 nM ARF; ○ and □, without ARF. (B) Time course of PLD reaction. •, with 56 nM G_M2 ganglioside activator and 200 nM ARF; ■, with 56 nM heat-stable PLD activator and 200 nM ARF; ○, with 200 nM ARF alone.