Table 5B. qRT-PCR validation of alternative splicing of 3 selected genes.
Disease Stage | Gene Symbol | Accession Number | Splicing Index (SI) | |||
---|---|---|---|---|---|---|
HTA 2.0 | qRT-PCR | |||||
Normal vs. HCV+ | CA | AA | CA | AA | ||
SAA1 | NM_000331 | 10.77 | NA | 9.12 | 3.21* | |
AOX1 | NM_001159 | -2.55 | NA | -2.10 | -1.38 | |
SLC13A5 | NM_001143838 | -1.37 | NA | -1.61 | -1.12 |
CA: Caucasian American; AA: African American.
*p<0.05; mean average of 3 biological replicates from each cohort.