Table 3. Univariate and multivariate analysis of factors associated with recurrence-free survival.

Variables	Univariate		Multivariate
	Hazard ratio	P	Hazard ratio	95% CI	P
NLR		0.008			0.07
Low NLR (≤1.7) High NLR (>1.7)	1 1.446		1 1.319	0.978-5.087
LMR Low LMR (≤6.8) High LMR (>6.8)	1 0.53	0.008	1 0.658	0.405-1.070	0.092
PLR Low PLR (≤92.88) High PLR (>92.88)	1 0.765	0.076	1 0.649	0.473-0.89	0.007
ypT stage		<0.001			<0.001
ypT0	1		1
ypT1 ypT2 ypT3 ypT4	0.388 1.852 5.216 6.235		0.417 1.694 3.297 3.208	0.097-1.799 0.972-1.449 1.980-5.491 0.74-14.7
ypN stage ypN0 ypN1 ypN2	1 2.931 5.347	<0.001	1 1.882 2.345	1.385-2.557 1.538-3.575	<0.001
Lymphovascular invasion	3.637	<0.001	1.762	1.229-2.526	0.002
Perineural invasion	3.195	<0.001	1.509	1.093-2.083	0.012
Age, yrs ≤70 >70	1 1.09	0.648
Gender Male Female	1 0.893	0.431

NLR, neutrophil to lymphocyte ratio; LMR, lymphocyte to monocyte ratio; PLR, platelet to lymphocyte ratio