Figure 7.
Bicyclic peptide libraries synthesized by mRNA display and SICLOPPS. a) Scheme showing the key features of the mRNA display technology; b) bicyclization of mRNA displayed peptides by the method of Sako et al.;[36] c) bicyclization of mRNA displayed peptide library by the method of Hacker et al.;[37] and d) bicyclization of SICLOPPS-synthesized peptides by the method of Bionda and Fusan.[39]