Figure 4.

The nine-gene signature associates with reductions in DFS in training and testing cohorts. See Table 3 for the identities of nine genes and the types of genomic alterations being tested in the signature. The signature was evaluated in 10 individual sets of training and testing populations; typical results in 2 cohort sets are shown. Kaplan-Meier and log-rank tests were performed using the R Survival Package. Recurr, recurrence; T, total. For training cohort, n = 300; for testing cohort, n = 185.