Supplementary Figure 5.

Mutations in β-catenin in D32, T41, and N387 significantly shorten overall survival in patients with metastatic prostate cancer. Data were extracted from the Michigan data set [22] (cBioPortal). (A) The three missense mutations and their associated OS are indicated. (B) Kaplan-Meier analysis of OS time in metastatic PCs with and without the missense mutations in β-catenin. Statistical analysis was performed using log-rank test. Both analyses were carried out using the tools provided by cBioPortal. Total#, total number of cases; dec#, number of deceased cases; MMS, median months survival.