Evolution. In the article “The role of robustness and changeability on the origin and evolution of genetic codes” by Tetsuya Maeshiro and Masayuki Kumura, which appeared in number 9, April 28, 1998, of Proc. Natl. Acad. Sci. USA (95, 5088–5093), the authors wish to note the following error in Table 2 related to the initiation codons of nuclear mycoplasma. They should read: AUG, GUG, and UUG [Dybvig, K. & Voelker, L. L. (1996) Annu. Rev. Microbiol. 50, 25–57]. Consequently, CMy (page 5091, last paragraph, right column) should be deleted in the text. These corrections do not change the results of the paper. A corrected Table 2 is shown below.
Table 2.
Representative genetic system | Code | Changes from SGC
|
Initiation codons | ||
---|---|---|---|---|---|
Codon | Phenotype | ||||
Mitochondrial yeasts | MYe | UGA | stop ⇒ Trp | AUG | 1 |
AUA | Ile ⇒ Met | ||||
CUN | Leu ⇒ Thr | ||||
Mitochondrial platyhelminths | MPl | UGA | stop ⇒ Trp | AUG | 1 |
AAA | Lys ⇒ Asn | ||||
AGR | Arg ⇒ Ser | ||||
UAA | stop ⇒ Tyr | ||||
Mitochondrialnematoda | MNe | UGA | stop ⇒ Trp | AUN UUG GUG | 6 |
arthropoda | AGR | Arg ⇒ Ser | |||
mollusca | AUA | Ile ⇒ Met | |||
Mitochondrial echinodermata | MEc | UGA | stop ⇒ Trp | AUG | 1 |
AAA | Lys ⇒ Asn | ||||
AGR | Arg ⇒ Ser | ||||
Mitochondrial tunicata | MTu | UGA | stop ⇒ Trp | AUG | 1 |
AUA | Ile ⇒ Met | ||||
AGR | Arg ⇒ Gly | ||||
Mitochondrial vertebrata | MVe | UGA | stop ⇒ Trp | AUN GUG | 5 |
AUA | Ile ⇒ Met | ||||
AGR | Arg ⇒ stop | ||||
Mitochondrial euascomycetes | MEu | UGA | stop ⇒ Trp | AUN NUG UUA | 8 |
Nuclear mycoplasma | CMy | UGA | stop ⇒ Trp | AUG GUG UUG | 3 |
Nuclear euplotes | CEu | UGA | stop ⇒ Cys | AUG | 1 |
Nuclear acetabularia | CAc | UAR | stop ⇒ Gln | AUG | 1 |
Nuclear blepharisma | CBl | UAG | stop ⇒ Gln | AUG | 1 |
Nuclear candida | CCa | CUG | Leu ⇒ Ser | AUG CUG | 2 |
Nuclear bacterial | CBa | — | — | AUN NUG | 7 |
N denotes any of A, U, G, and C, and R denotes A and G. The values in the initiation codons indicate the number of known initiation codons. The codon reassignments of each deviant code are arranged from top to bottom in the estimated order of reassignments. Compiled from http://www3.ncbi.nlm.nih.gov/htbin-post/Taxonomy/wprintgc?mode=c.