Up-regulated |
hsa04110: Cell cycle |
20 |
11.8 |
1.94E-16 |
CDC6, CDK1, SKP2, TTK, CHEK1, ESPL1, PTTG1, MCM4, CCNB1, CCNE2, MAD2L1, MCM7, CCNB2, BUB1, PCNA, BUB1B, MDM2, GADD45A, CCNA2, BUB3 |
hsa04115: p53 signaling pathway |
10 |
5.9 |
9.04E-08 |
BID, CCNB1, CCNE2, CDK1, CCNB2, RRM2, MDM2, CHEK1, PMAIP1, GADD45A |
hsa03030: DNA replication |
7 |
4.1 |
3.92E-06 |
RFC5, RFC3, MCM7, POLD1, POLE, PCNA, MCM4 |
hsa05222: Small cell lung cancer |
9 |
5.3 |
7.66E-06 |
CCNE2, CKS1B, COL4A2, COL4A1, ITGAV, CKS2, SKP2, LAMB1, FN1 |
hsa04512: ECM-receptor interaction |
7 |
4.1 |
6.20E-04 |
COL4A2, COL4A1, ITGAV, HSPG2, LAMB1, FN1, HMMR |
hsa05200: Pathways in cancer |
14 |
8.3 |
8.32E-04 |
BID, WNT5A, CKS1B, COL4A2, COL4A1, SKP2, BIRC5, MECOM, CCNE2, ITGAV, CKS2, MDM2, LAMB1, FN1 |
hsa04114: Oocyte meiosis |
7 |
4.1 |
2.0E-03 |
CCNE2, CDK1, MAD2L1, BUB1, AURKA, ESPL1, PTTG1 |
hsa03420: Nucleotide excision repair |
5 |
3.0 |
2.4E-03 |
RFC5, RFC3, POLD1, POLE, PCNA |
hsa03430: Mismatch repair |
4 |
2.4 |
2.6E-03 |
RFC5, RFC3, POLD1, PCNA |
hsa04914: Progesterone- mediated oocyte maturation |
6 |
3.6 |
4.0E-03 |
CCNB1, CDK1, MAD2L1, CCNB2, BUB1, CCNA2 |
hsa05166: HTLV-I infection |
9 |
5.3 |
0.012 |
WNT5A, MAD2L1, POLD1, POLE, PCNA, BUB1B, CHEK1, PTTG1, BUB3 |
hsa04068: FoxO signaling pathway |
6 |
3.6 |
0.023 |
CCNB1, SGK1, CCNB2, SKP2, MDM2, GADD45A |
hsa00670: One carbon pool by folate |
3 |
1.8 |
0.024 |
TYMS, SHMT2, DHFR |
hsa00240: Pyrimidine metabolism |
5 |
3.0 |
0.037 |
TYMS, UMPS, POLD1, RRM2, POLE |
hsa05203: Viral carcinogenesis |
7 |
4.1 |
0.038 |
CCNE2, CDK1, SKP2, MDM2, CHEK1, PMAIP1, CCNA2 |
Down-regulated |
hsa05016: Huntington's disease |
8 |
3.4 |
2.0E-03 |
DNAH9, DNALI1, DNAI1, CREBBP, DNAH3, DNAH2, DNAH7, DNAH6 |
hsa01100: Metabolic pathways |
20 |
8.5 |
0.016 |
GDA, ADSSL1, GMDS, GNE, DHRS9, ADH7, COMT, CDS1, AK7, AGMAT, MAN1C1, ALDH3A1, DGKA, ALOX15, ATP6V0E2, GCK, FUT3, MGLL, FUT2, ATP6V0A4 |
hsa00982: Drug metabolism–cytochrome P450 |
4 |
1.7 |
0.026 |
FMO5, GSTA3, ADH7, ALDH3A1 |
hsa04530: Tight junction |
5 |
2.1 |
0.040 |
PRKCA, CGN, MYH11, CLDN10, CLDN23 |
hsa00350: Tyrosine metabolism |
3 |
1.3 |
0.042 |
ADH7, COMT, ALDH3A1 |