Commentary. In the article “Neurodegenerative diseases and transglutaminase” by Laszlo Lorand, which appeared in number 25, December 10, 1996, of Proc. Natl. Acad. Sci. USA (93, 14310–14313), the author requests that the following correction be noted. In Fig. 2, reaction (V) for the hydrolysis of the isopeptide should read as follows: