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Examples of the manual segmentations on two HCs and two MS patients generated by the two raters following the protocol outlined in Sec. 2.2 and described in detail in Appendix A. Colored voxels are boundary voxels of the thalamus. The color of the contour indicates the absolute minimum distance from a voxel on the surface generated by one rater to the surface of the other rater, with the scale of the distance shown in the color bar in the bottom row.
