Genetics. In the article “Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin” by Stella E. Tsirka, Thomas H. Bugge, Jay L. Degen, and Sidney Strickland, which appeared in number 18, September 2, 1997, of Proc. Natl. Acad. Sci. USA (94, 9779–9781), the authors request that the following correction to Fig. 1 be noted. Due to a printer’s error, Fig. 1 was highly pixelated with extremely poor contrast. A corrected version with higher contrast is reproduced below.

Figure 1.

Plasmin functions in neuronal cell death independently of fibrin clearance. Cresyl violet-stained coronal sections through the hippocampus reveal the neuronal degeneration generated 5 days after KA injection. (Upper Left) Hippocampus from heterozygous plg^+/−;fib^+/− mouse (wt) showing substantial degeneration on the injected side (ipsilateral). CA1, CA2, and CA3 denote the hippocampal subfields. (Upper Right) Hippocampus from plg^−/− mouse showing minimal degeneration on the injected side. (Lower Left) Hippocampus from fib^−/− mouse showing extensive degeneration on the injected side. (Lower Right) Hippocampus from plg^−/−;fib^−/− mouse showing minimal degeneration on the injected side. In each case, the uninjected side (contralateral) showed no detectable degeneration. Arrows show the site of injection. The genotypes were coded until completion of the experiments and scoring of the results.