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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1999 Sep 14;96(19):10944.
PMCID: PMC56172

Genetics. In the article “Neurosecretory control of aging in Caenorhabditis elegans” by Michael Ailion, Takao Inoue, Carole I. Weaver, Robert W. Holdcraft, and James H. Thomas, which appeared in number 13, June 22, 1999, of Proc. Natl. Acad. Sci. USA (96, 7394–7397), the following corrections should be noted.

(i) Figs. 1 and 2 were interchanged. The figure legends are correct, but the figures were transposed. The corrected figures and their legends are shown below. (ii) In Table 2, line 2, the genotype of the strain should be unc-64(e246), not unc-63(e246). (iii) Table 1 originally had blank lines separating the top, middle, and bottom sections of the table. Without these spaces, it is difficult to tell what is referred to as top, middle, and bottom in the table legend. Top refers to lines 1–6, middle refers to lines 7–8, and bottom refers to lines 9–12.

Figure 1.

Figure 1

unc-64 and unc-31 mutants have increased life spans and are suppressed by daf-16. Assays were performed at 20°. unc-64 and unc-31 have significantly longer life spans than N2 (P < 0.0001 for unc-64 and P = 0.0004 for unc-31). This figure uses the same data set as Table 1.

Figure 2.

Figure 2

Mutations in unc-64 and unc-31 do not enhance the longevity of daf-2 mutants. Animals were grown at 15° to allow development past the dauer stage and then were shifted to 20°. unc-64; unc-31 had a significantly longer life span than either unc-64 (P = 0.0002) or unc-31 (P = 0.0005). The daf-2 unc-64 double mutant and daf-2 were not significantly different (P = 0.5139). The maximum life span of daf-2 unc-64 was extended to >100 days by a single animal. We have not investigated whether this has any possible significance. This figure uses the same data set as Table 2.


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