Figure 1. Validation of SRPK1 expression in gastric cancer tissues.

(A) SRPK1 protein expression as determined in an IHC assay of tissues from patients with gastric adenocarcinoma. Among 158 patients, tissues from 83 showed high SRPK1 staining, mainly in the cytoplasm and partly in the nucleus of cancer cells (IHC score≥8). Moreover, both the protein (B) and RNA (C) levels of SRPK1 in gastric adenocarcinoma tissues were positively correlated with tumor stage (P<0.001 and P=0.047, respectively). Data was from three independent experiments and statistical analyzes were conducted with One-way ANOVA test, P value was showed correspondingly.