TABLE 3.
Treatment of Behaviors in FXS+ASD and FXS only, by Age Group, in Subjects Enrolled From September 7, 2012 Through August 31, 2014, FORWARD Database
| Ages 3–11 y | Ages 12–21 y | |||||
|---|---|---|---|---|---|---|
| Is This Behavior Being Treated With Medicationa,b: N (%) | FXS+ASD (N = 111) | FXS Only (N = 164) | P | FXS+ASD (N = 52) | FXS Only (N = 70) | P |
| Anxiety | 39 (35) | 43 (26) | <.11 | 33 (64) | 40 (57) | <.48 |
| Aggression/disruptive behavior | 36 (32) | 18 (11) | <.001c | 32 (62) | 21 (30) | <.001c |
| Attention problems | 29 (26) | 49 (30) | <.50 | 24 (46) | 33 (47) | <.91 |
| Depression | 9 (8) | 7 (4) | <.18 | 10 (19) | 12 (17) | <.77 |
FORWARD is a data set of clinician and parent-report information from specialty clinics in the FXCRC. χ2 tests for association were used to obtain P values for differences in proportions between case groups for use of services.
a
Only subjects on investigational drugs were excluded from the analyses.
b
Subjects in FXS+ASD and FXS-only groups could be treated for >1 behavior.
c
Significant P value (a level of .05 was considered statistically significant).