Table 3. Adjusted hazard ratios (HRs) for recurrence by age and hormone receptor status, from five Cox regression models.

Variable	Age					Hormone receptor				p
	Model 1a		Model 2ab		Model 2bc		Model 3ad		Model 3be
			<65 years		≥65 years		Positive		Negative
	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)
Deprivation index tertile
1 (least)	1		1		1		1		1
2	1.07 (0.86-1.34)	0.52	1.13 (0.85-1.50)	0.40	1.00 (0.71-1.42)	0.98	1.18 (0.85-1.63)	0.98	0.83 (0.55-1.26)	0.40
3 (most)	1.18 (0.96-1.46)	0.11	1.29 (0.99-1.68)	0.06	1.04 (0.74-1.46)	0.83	1.44 (1.07-1.93)	0.02	0.74 (0.49-1.14)	0.17
Stage
Early	1		1		1		1		1
Late	3.29 (2.69-4.03)	<0.01	3.05 (2.37-3.92)	<0.01	3.72 (2.64-5.24)	<0.01	3.13 (2.36-4.15)	<0.01	3.78 (2.54-5.62)	<0.01
Unknown	1.63 (1.13-2.37)	<0.01	1.77 (1.06-2.98)	0.03	1.57 (0.92-2.70)	0.10	2.17 (1.23-3.81)	<0.01	1.69 (0.71-4.05)	0.24
Age
<65 years	1		-	-	-	-	1		1
≥65 years	0.98 (0.81-1.18)	0.86	-	-	-	-	0.95 (0.73-1.23)	0.70	1.03 (0.72-1.48)	0.86
Hormone receptor status
Positive	1		1		1		-	-	-	-
Negative	2.41 (1.95-2.98)	<0.01	2.31 (1.76-3.02)	<0.01	2.59 (1.82-3.70)	<0.01	-	-	-	-
Other or unknown	1.52 (1.21-1.90)	<0.01	1.48 (1.11-1.97)	<0.01	1.58 (1.11-2.24)	0.01	-	-	-	-

^aAll cases (3,358) were included in this model. ^b1893 cases aged <65 years were selected for this model adjusted for stage and hormone receptor status. ^c1465 cases aged ≥65 years were selected for this model adjusted for stage and hormone receptor status. ^d2,024 hormone receptor-positive cases were selected for this model adjusted for stage and age. ^e543 hormone receptor-negative cases were selected for this model adjusted for stage and age.