Table 1. Cardiac function assessment by 2-D echocardiography.
| 2-D Echo | 0 week | 4 weeks | ||
|---|---|---|---|---|
| Sham (n = 6) | MI (n = 6) | NC (n = 6) | Myoblasts (n = 6) | |
| LVIDd (mm) | 32.3 ± 3.6 | 37.2 ± 4.2 | 37.4 ± 5.1 | 36.3 ± 3.8 |
| LVIDs (mm) | 21.3 ± 2.5 | 28.6 ± 3.2 | 27.1 ± 2.3 | 26.9 ± 2.9* |
| LVEDV (ml) | 43.6 ± 4.7 | 56.8 ± 4.3 | 57.7 ± 4.9 | 55.2 ± 4.6 |
| LVESV (ml) | 16.2 ± 1.7 | 31.2 ± 2.4 | 31.3 ± 1.8 | 26.3 ± 2.1* |
| FS (%) | 34.8 ± 3.6 | 21.4 ± 1.5 | 22.7 ± 1.2 | 27.6 ± 2.2* |
| EF (%) | 64.1 ± 5.5 | 44.8 ± 4.2 | 46.3 ± 5.2 | 52.1 ± 4.7* |
| LVPWs (mm) | 13.5 ± 0.3 | 6.5 ± 0.4 | 6.4 ± 0.5 | 10.4 ± 0.4* |
| LVPWd (mm) | 8.3 ± 0.4 | 5.1 ± 0.3 | 5.3 ± 0.4 | 6.6 ± 0.2* |
The assessment of cardiac function of minipigs with MI or sham operation at 1 month after myoblast transplantation, control treatment (NC) or left untreated. *P < 0.05 vs. control treatment group. LVIDd: left ventricular end-diastolic internal diameter; LVIDs: left ventricular end-systolic internal diameter; LVEDV: left ventricular end-diastolic volume; LVESV: left ventricular end-systolic volume; FS: fractional shortening; EF: ejection fraction; LVPWs: Left ventricular end-systolic posterior wall thickness; LVPWd: Left ventricular end-diastolic posterior wall thickness.